藥品異動通知及新藥介紹

14N028 Nipride(50mg)inj.因廠商不生產故用完DC新增<14N060> Nicardipine (Perdipine®) 10mg/10ml/Amp替代

新藥介紹

<14N060> Nicardipine (Perdipine®) 10mg/10ml/Amp

作用機轉/

藥理作用

 

Nicardipine hydrochloride is a calcium channel antagonist that

inhibits the transmembrane influx of calcium ions into

myocardium and selectively into coronary vascular smooth

muscles without altering serum calcium concentrations.

In the process, it affects the contractile functions of cardiac and

vascular smooth muscle .

適應症/劑量

IV infusion,

Adult

Post-operative hypertension:

2-10 mg/kg/min guided by patient response.

Malignant hypertension:

0.5-6 mg/kg/min guided by patient response.

Pediatric

Safety and effectiveness have not been established.

注意事項

Diluted with 0.9%NS or 5%G/W to 0.1-0.2mg/ml,

IV infusion at a rate according to the blood pressure.

使用禁忌

advanced aortic stenosis,

asphyxia (perinatal),

hypersensitivity to nicardipine/calcium channel antagonists.

不良反應

M: Flushing.

L: Angina; hypotension; peripheral edema; dizziness; headache; nausea; weakness; headache; tachycardia.

R: Skin rash; CHF or pulmonary edema; constipation; diarrhea; bradycardia, extrapyramidal effect; gingival enlargement; mental depression; dryness of mouth.

懷孕危險分級

C

健保規範

無相關規定。

 

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