Related Posts with Thumbnails     Say遊記     奇美醫院        食品藥物消費者知識服務網    台灣藥事資訊網    正確用藥數位資訊學習網
柳營奇美醫院24小時藥物諮詢電話:06-6226999-77119 email:clh5500@mail.chimei.org.tw

目前日期文章:200807 (4)

瀏覽方式: 標題列表 簡短摘要

一、  藥品新增

<24L081> Lercanidipine (Zanidip ® ) 10mg/ F.C Tab.

 

二、  新藥介紹

<24L081> Lercanidipine (Zanidip ® ) 10mg/ F.C. Tab.

作用機轉/

藥理作用

 

Lercanidipine, a dihydropyridine calcium antagonist, has a high affinity for and competitively antagonizes the dihydropyridine subunit of the L-type calcium channel.

Lercanidipine lowers blood pressure by relaxing arteriolar smooth muscle, which decreases peripheral vascular resistance. Lercanidipine produces no negative cardiac inotropism and only mild reflex tachycardia

適應症/劑量

PO,

Adult

Hypertension:

Initial 10 mg QD; maintenance, 10-20 mg QD. Max. 30 mg/d.

Pediatric

Safety and efficacy have not been established.

注意事項

Take 15 minutes before meals.

使用禁忌

hypersensitivity to lercanidipine or other dihydropyridine

preparations;

left ventricular outflow tract obstruction,

untreated congestive cardiac failure,

unstable angina pectoris,

severe renal or hepatic dysfunctions;

within 1 month of a myocardial infarction.

不良反應

Peripheral edema, dizziness, lightheadedness, flushing, feeling

of warmth, headache, nausea.

懷孕危險分級

Unknown

健保規範

無相關規定

 

 

 

藥劑科  

Sam080477 發表在 痞客邦 PIXNET 留言(0) 人氣()

藥品異動通知及新藥介紹

一、  藥品新增

<25A066> Ambroxol (Soltan® ) Liquid 3mg/ ml, 100ml/Btl

<25F029> Fenoterol (Strolin® ) Liquid 0.5mg/ ml, 60ml/Btl

<27P110> Prednisolone (Kidsolone® ) Oral Sol’n 1mg/ ml, 60ml/Btl

 

二、  新藥介紹

 

<25A066> Ambroxol (Soltan ® ) Liquid 3mg/ ml, 100ml/Btl

作用機轉/

藥理作用

 

Ambroxol, an active N-desmethyl metabolite of the mucolytic bromhexine, 1)increases the quantity and decrease the viscosity of tracheobronchial secretions, 2)acts as an expectorant, increasing mucociliary transport via stimulation of ciliary motility, 3) stimulates the synthesis and secretion of pulmonary surfactant, 4) decreases airway hyper-reactivity by either increasing lysophosphatidyl-choline turnover and/or modifying epithelial secretions, 5) attributes antioxidative characteristics by reducing reactive oxygen species (ROS) produced by activated human polymorphonuclear cells (PMN) and reducing the prooxidative metabolism of inflammatory cells.

適應症/劑量

PO,

Adult & Pediatric

Expectorant:

Adult and Pediatric12yrs: 10ml TID.            

Pediatric,

6-12yrs: 5ml TID,

2-6yrs: 2.5ml BID-TID,

< 2yrs: 2.5ml BID.

使用禁忌

contraindications have not been determined.

不良反應

Mild GI effect & allergic reactions.

懷孕危險分級

N

健保規範

無相關規定

 

 

 

<25F029> Fenoterol (Strolin ® ) Liquid 0.5mg/ ml, 60ml/Btl

作用機轉/

藥理作用

Fenoterol is a higher selectivity full beta-2 adrenergic agonist appears to have negligible alpha-adrenergic agonist activity and minimal beta-1 adrenergic agonist activity.

適應症/劑量

PO,

Adult & Pediatric

Bronchospasm:

Adult and Pediatric14yrs:5-10ml TID.

Pediatric,

6-14yrs: 5ml TID, 

1-6yrs: 2.5-5ml TID, 

< 1yrs: 2.5ml BID.

使用禁忌

hypersensitivity to fenoterol, other product components, or other

sympathomimetic amines;

hyperthyroidism;

hypertrophic obstructive cardiomyopathy

tachyarrhythmia.

不良反應

M: Fast heartbeat; headache; nervousness; trembling

L: Coughing; dizziness or light-headedness; dryness or irritation

of mouth or throat; chest discomfort; drowsiness; hypokalemia;

irregular heartbeat; muscle cramps or twitching; N/V;

oropharyngeal irritation; restlessness; trouble in sleeping; taste

change; nervousness; tingling in extremities; numbness; tremor

R: dermatitis.

懷孕危險分級

N

健保規範

無相關規定

 

  

<27P110> Prednisolone (Kidsolone ® ) Oral Sol’n 1mg/ ml, 60ml/Btl

作用機轉/

藥理作用

 

Prednisolone sodium phosphate is a synthetic adrenocortical steroid that predominantly exerts glucocorticoid effects like promotion of gluconeogenesis, increased deposition of glycogen in the liver, inhibition of the utilization of glucose, anti-insulin activity, increased protein catabolism, increased lipolysis, stimulation of fat synthesis and storage, and increased urate and calcium excretion.

The drug reduces eosinophil and lymphocyte production, stimulates erythropoiesis and production of polymorphonuclear lymphocytes and inhibits inflammation and wound healing.

It induces the secretion of gastric juice components and possesses a slight mineralocorticoid activity

適應症/劑量

PO,

Adult

Corticosteroid: 5-60 ml/d QD or in divided doses.

Acute exacerbations of multiple sclerosis:

200 ml/d for 1 wk, followed by 80 ml QOD for 1 month.

Max. 250 ml/d

Pediatric

Adrenocortical insufficiency: 0.14 ml/kg or 4 ml/m2/d in 3 divided doses.

Usual dose: 0.5-2 ml/kg or 15-60 ml/m2/d in 3or4 divided doses.

使用禁忌

systemic fungal infections;

hypersensitivity to prednisolone or its components;

live of live attenuated vaccines (immunosuppresive doses).

不良反應

M: GI irritation; increased appetite;indigestion; nervousness or restlessness; trouble in sleeping; weight gain

L: Diabetes mellitus

R: CHF; generalized allergic reaction; psychic disturbances such as delirium, disorientation, euphoria, hallucinations, manic-depressive episodes, mental depression, or paranoia.

懷孕危險分級

C

 

 

 

藥劑科  

Sam080477 發表在 痞客邦 PIXNET 留言(1) 人氣()

藥品異動通知及新藥介紹

一、    藥品新增

<25M060> Dextromethorphan/ Potassium cresolsulfonate (Medicon ® )Syrup, 60ml/Btl

 

二、    新藥介紹

<25M060> Medicon ® Syrup  60ml/Btl

Each ml contains:
Dextromethorphan HBr 2.5 mg+ potassium cresolsulfonate15 mg

作用機轉/

藥理作用

Dextromethorphan exerts antitussive effect by acting centrally on the respiratory center in the medulla and nucleus tractus solaris to increase the cough threshold.

Potassium cresolsulfonate acts as an expectorant.

適應症/劑量

PO,

Adult

Antitussive & expectorant: : 18-24ml/day in 3-4 divided doses.

Pediatric

Antitussive & expectorant: :

8-14yrs: 9-16ml/day in 3-4 divided doses.

3mo-7yrs: 3-8ml/day in 3-4 divided doses.

使用禁忌

during or within 14 days of discontinuing MAOI  therapy

because of risk of serotonin syndrome;

known hypersensitivity to the drug or any ingredient in the

formulation.

不良反應

Dizziness; GI upset; drowsiness.

懷孕危險分級

Dextromethorphan HBr: C

健保規範

無相關規定

 

 

 

 

藥劑科  

Sam080477 發表在 痞客邦 PIXNET 留言(0) 人氣()

一、 各單位如備有11G033 Gentamycin 40mg/ml,10ml/vial包裝庫存用完,藥局即不做公藥撥補,此藥刪除。

二、 新進11G059 Gentamycin 40mg/ml,2ml/vial小包裝生達廠,比照其它針劑處方,藥局直接發藥,不再做累積公藥撥補。

 

 

 

藥劑科  

Sam080477 發表在 痞客邦 PIXNET 留言(0) 人氣()

找更多相關文章與討論