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目前日期文章:200812 (4)

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藥品新增

<11F139> Flomoxef (Flumarin ® ) 1gm/ Vial

健保給付規定

依中央健保局藥品給付規定第十章『抗微生物劑用藥給付規定通則』實施。

刪除品項

 <11F105> Flomoxef (Flumarin ® ) 0.5gm/ Vial 品項用完刪除。

藥劑科藥管組啟

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幼兒自費六合一疫苗Infanrix hexa (學名DTPA-HBV-HIB-POLI  藥品代號11D101)已恢復供貨。

藥劑科藥管組 啟

 

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免費小兒流感疫苗(Vaxigrip 0.25ml 藥品代號11V070);免費成人流感疫苗Fluvirin(藥品代號11V054 ) ,用罄為止結束施打!!! 疾管局不再供貨!!!未施打的病患請洽各地衛生所!!!

 

 

 

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藥品新增

<21C137> Clarithromycin (Klaricid ® ) Oral Suspension  25mg/ml, 70ml/Btl

 

新藥介紹 

<21C137> Clarithromycin (Klaricid®)Oral Susp.  25mg/ml, 70ml/Btl

作用機轉/

藥理作用

 

Clarithromycin, a semisynthetic macrolide antibiotic, inhibits protein synthesis in susceptible organisms by penetrating the cell wall and binding to 50S ribosomal subunits, thereby inhibiting translocation of aminoacyl transfer-RNA and inhibiting polypeptide synthesis.

適應症/劑量

PO,

Adult

Chronic bronchitis, bacterial exacerbations due to Haemophilus influenzae:20ml q12h for 7- 14 days.

Chronic bronchitis, bacterial exacerbations due to Haemophilus parainfluenzae: 20ml q12h for 7 days.

Chronic bronchitis, bacterial exacerbations due to M. catarrhalis, or S pneumoniae; uncomplicated skin and soft tissue infections:20ml q12h for 7- 14 days.

Disseminated Mycobacterium avium complex disease, prophylaxis :20ml BID.

Disseminated Mycobacterium avium complex disease:

20ml BID in combination with other antimycobacterial agents; clarithromycin therapy should continue for life if clinical and mycobacterial improvements are observed.

Pharyngitis, streptococcal or tonsillitis:10ml q12h for 10 days.

Community-acquired pneumonia, due to C pneumoniae, M. pneumoniae, or S pneumoniae:10ml q12h for 7- 14 days.

Community-acquired pneumonia, due to H. influenzae:

10ml q12h for 7 days.

Community-acquired pneumonia, due to H. parainfluenzae, or M. catarrhalis:40ml QD for 7 days.

Acute maxillary Sinusitis:20ml q12h for 14 days.

Pediatric

Acute otitis media; streptococcal pharyngitis; community-acquired pneumonia, due to C. pneumoniae, M. pneumoniae, or S pneumoniae; Sinusitis, acute maxillary; Skin and soft tissue infections; Tonsillitis:

7.5 mg/kg q12h for 10 days

Disseminated Mycobacterium avium complex disease:

7.5 mg/kg, up to 20ml BID

Disseminated Mycobacterium avium complex disease:

7.5 mg/kg, up to 20ml BID in combination with other antimycobacterial agents; clarithromycin therapy should continue for life if clinical and mycobacterial improvements are observed

Max. 40 ml/day

注意事項

1)      Take without regard to food.

2)      Reconstitute with 37ml drink water, shake well to make a 125mg/5ml of  70ml suspension.

3)      After reconstitution, the oral suspension may be stored at

25℃ for 14 days; don't  refrigerate the reconstituted suspension.

使用禁忌

 known hypersensitivity to clarithromycin, erythromycin, or any other macrolide antibiotic.

不良反應

L: Infection; abnormal sensation of taste; dyspepsia; flatulence; GI disturbances; headache.

R: Hepatotoxicity; hypersensitivity reaction; pseudomembranous colitis; thrombocytopenia.

懷孕危險分級

C

健保規範

1)      限用於經臨床診斷或實驗室診斷為黴漿菌(mycoplasma)或披衣菌(chlamydia)或退伍軍人桿菌(legionella)引起之感染、或經培養證實為macrolides有效之致病菌感染(需於病歷記載診斷依據,俾利審查)。

2)      使用期間不得超過十日,每日最大劑量500mg。

3)      本類製劑應儘量避免合併使用其他抗生素。

 

藥品圖檔

21C137.JPG 

                                     

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