藥品刪除

<24C115> Cilostazol (Pletaal® ) Tab. 50mg

  

藥品新增

<35A031> Azelastine HCl (Azela ® ) Nasal Spray  0.1%; 0.14mg/dose,100dose/Btl

<24C131> Cilostazol (Pletaal® ) Tab. 100mg

新藥介紹

<35A031> Azelastine HCl (Azela ®)Nasal Spray 0.1%; 0.14mg/dose,100dose/Btl

作用機轉/

藥理作用

 

Azelastine HCl, a relatively selective H(1)-antagonist, blocks

release of histamine from cells involved in the allergic response.

It also demonstrates inhibition of other mediators involved in allergic reactions (eg, leukotrienes and platelet-aggregating factor (PAF)), and reduction of chemotaxis and eosinophil activation .

適應症/劑量

Adult

Seasonal allergic rhinitis: 1 or 2 sprays per nostril twice daily.

Vasomotor rhinitis: 2 sprays per nostril twice daily.

Pediatric

Seasonal allergic rhinitis:

5 to 11 yrs, 1 spray per nostril twice daily.

12 yrs and over, 1 or 2 sprays per nostril twice daily.

Vasomotor rhinitis: over 12 yrs, 2 sprays per nostril twice daily.

使用禁忌

concurrent use of alcohol or other CNS depressants,

hypersensitivity to azelastine products.

不良反應

Bitter taste in mouth; nasal stinging/burning; somnolence,

headache; fatigue.

懷孕危險分級

C

健保規範

無相關規定

藥品圖檔

35A031.JPG 

新藥介紹

<24C131> Cilostazol (Pletaal® ) Tab. 100mg

藥理作用

1)Quinolinone-derivative selective phosphodiesterase (PDE) type 3 inhibitor; platelet-aggregation inhibitor and arterial vasodilator.

2)Appears to inhibit activation of cellular PDE type 3, resulting in suppressed degradation and increased concentrations of cAMP in platelets and blood vessels. Increased cAMP levels appear to mediate arterial vasodilation and inhibition of platelet aggregation.

3)Favorably alters concentrations of certain lipoproteins; reduces plasma triglycerides and increases high-density lipoprotein (HDL)-cholesterol concentrations. No effect on plasma concentrations of total cholesterol, low-density lipoprotein (LDL)-cholesterol, or lipoprotein(a) (Lp[a]).

適應症/劑量

PO,

Adult

Intermittent Claudication100mg BID.

Pediatric

Safety and efficacy not established.

給藥注意事項

Take 30 minutes before meals, or 2 hours after meals.

使用禁忌

congestive heart failure of any severity;

hemostatic disorders or active pathologic bleeding, such as

bleeding peptic ulcer or intracranial bleeding;

known hypersensitivity to cilostazol products.

懷孕危險分級

C

不良反應

M: Fever; tachycardia; abdominal pain; back pain; GI effects; dizziness; headache; cough; myalgia; nausea; peripheral edema; pharyngitis; rhinitis.

L: Atrial fibrillation; CHF; abnormal bleeding; anemia; neck rigidity; tongue edema; purpura; urticaria; syncope; arthralgia; gastroenteritis; esophagitis; postural hypotension; tinnitus.

健保規範

限使用於緩解間歇性跛足的症狀。

   

原<24C115> Cilostazol (Pletaal® ) Tab. 50mg 品項刪除。

藥品圖檔

24C131.JPG 

藥劑科藥管組

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