藥品新增

<17K047> Kabiven® Emulsion For Injection 1440ml

 

新藥介紹

<17K047> Kabiven® Emulsion For Injection    NT 1176

Each 1440ml Kabiven® consists of a three chamber bag and an overpouch.

The individual chambers contain:

Glucose 11% 885 ml, Amino acids/electrolytes(Vamin 18) 300ml, Fat Emulsion (Intralipid) 20% 255 ml.

Total energy: approx. 1038 Kcal

作用機轉/

藥理作用

 

Fat emulsion provides essential and non-essential long chain fatty acids for energy metabolism and the structural integrity of cell membranes.

Amino acids, constituents of protein in ordinary food, are utilised for tissue protein synthesis and any surplus is channelled to a number of metabolic pathways. Studies have shown a thermogenic effect of amino acid infusion.

Glucose should have no pharmacodynamic effects apart from contributing to maintain or replete the normal nutritional status.

適應症/劑量

IV infusion,

Adult and Pediatric >10yr

Parenteral nutrition: 27 - 40 ml/kg/day, Max. 40 ml/kg/day.

Pediatric 2-10yr

Parenteral nutrition:14-28 ml/kg initially, and increased by 10-15 ml/kg/day up to a Max.of 40 ml/kg/day.

注意事項

1)The infusion rate should not exceed 3.7 ml/kg/hr (corresponding to 0.25 g glucose, 0.09 g amino acid and 0.13 g fat/kg). The recommended infusion period for individual bags of Kabiven is 12-24 hours.

2)After breaking the seals, chemical and physical in-use stability of the mixed three chamber bag has been demonstrated for 24 hours at 2-8°C or 25°C.

使用禁忌

hypersensitivity to egg-, soya- or peanut protein or to any of the ingredients;

severe hyperlipaemia;

severe liver insufficiency;

severe blood coagulation disorders;

inborn errors of amino acid metabolism;

severe renal insufficiency without access to haemofiltration or dialysis;

acute shock;

hyperglycaemia, which requires more than 6 units insulin/h;

pathologically elevated serum levels of any of the included electrolytes;

general contraindications to infusion therapy: acute pulmonary oedema, hyperhydration, decompensated cardiac insufficiency and hypotonic dehydration;

haemophagocytotic syndrome;

unstable conditions (e.g. severe post-traumatic conditions, uncompensated diabetes, acute myocardial infarction, metabolic acidosis, severe sepsis and hyperosmolar coma);

due to composition, Kabiven is not suitable for use in new-borns

or infants under 2 years of age.

不良反應

A rise in body temperature; shivering, chills; abdominal pain,

nausea/vomiting; transient increases in liver enzymes;

thrombophlebitis; hypersensitivity reactions (anaphylactic

reaction, skin rash, urticaria);respiratory symptoms (e.g.

tachypnoea); hyper/hypotension; haemolysis, reticulocytosis;

headache; tiredness.

懷孕危險分級

Unknown

健保規範

無相關規定。

其他

本藥品為小額採購品項。處方限醫師開立

藥品圖檔

17K047.JPG 

                                         

 

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